Identification and differentiation of PDX1 β-cell progenitors within the human pancreatic epithelium.

Abstract

AIM To minimize the expansion of pancreatic mesenchymal cells in vitro and confirm that β-cell progenitors reside within the pancreatic epithelium. METHODS Due to mesenchymal stem cell (MSC) expansion and overgrowth, progenitor cells within the pancreatic epithelium cannot be characterized in vitro, though β-cell dedifferentiation and expansion of MSC… (More)
DOI: 10.4239/wjd.v5.i1.59

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