Identification and cross-species comparison of canine osteoarthritic gene regulatory cis-elements.

Abstract

OBJECTIVE To better understand transcription regulation of osteoarthritis (OA) by examining common promoter motifs in canine osteoarthritic genes, to identify other genes containing these motifs and to assess the conservation of these motifs between canine, human, mouse and rat. DESIGN Differentially expressed transcripts in canine OA were mapped to the… (More)

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