Identification and charaterization of the second retinoic acid response element in the phosphoenolpyruvate carboxykinase gene promoter.

@article{Scott1996IdentificationAC,
  title={Identification and charaterization of the second retinoic acid response element in the phosphoenolpyruvate carboxykinase gene promoter.},
  author={Donald K Scott and Jerald A Mitchell and Daryl K. Granner},
  journal={The Journal of biological chemistry},
  year={1996},
  volume={271 11},
  pages={6260-4}
}
A previously characterized retinoic acid response element (RARE1) in the phosphoenolpyruvate carboxykinase (PEPCK) gene promoter confers approximately 50% of the response of this gene to retinoic acid (RA). Transient transfection experiments were performed using constructs containing progressive 5' deletions of the PEPCK promoter to locate other elements that contribute to the RA response. A second RARE (RARE2) was located between -402 and -306. Methylation interference and mobility gel shift… CONTINUE READING

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