Identification and characterization of two parathyroid hormone-like molecules in zebrafish.

@article{Gensure2004IdentificationAC,
  title={Identification and characterization of two parathyroid hormone-like molecules in zebrafish.},
  author={Robert C. Gensure and Bhaskar Ponugoti and Yasemin Gunes and Madhusudhan R Papasani and Beate Lanske and Murat Bastepe and David A. Rubin and Harald W Jueppner},
  journal={Endocrinology},
  year={2004},
  volume={145 4},
  pages={1634-9}
}
Zebrafish (Danio rerio) have receptors homologous to the human PTH (hPTH)/PTHrP receptor (PTH1R) and PTH-2 receptor (PTH2R) and an additional receptor (PTH3R) with high homology to the PTH1R. To find natural ligands for zPTH1R and zPTH3R, we searched the zebrafish genomic database and discovered two distinct regions that, when translated (zPTH1 and zPTH2… CONTINUE READING