Identification and characterization of two families of F420H2-dependent reductases from Mycobacteria that catalyse aflatoxin degradation

@inproceedings{Taylor2010IdentificationAC,
  title={Identification and characterization of two families of F420H2-dependent reductases from Mycobacteria that catalyse aflatoxin degradation},
  author={Matthew C Taylor and Colin J Jackson and David Bruce Tattersall and Nigel French and Thomas S. Peat and Janet Newman and Lyndall J. Briggs and Gauri V. Lapalikar and Peter M. Campbell and Colin T. Scott and Robyn J Russell and John G Oakeshott},
  booktitle={Molecular microbiology},
  year={2010}
}
Aflatoxins are polyaromatic mycotoxins that contaminate a range of food crops as a result of fungal growth and contribute to serious health problems in the developing world because of their toxicity and mutagenicity. Although relatively resistant to biotic degradation, aflatoxins can be metabolized by certain species of Actinomycetales. However, the enzymatic basis for their breakdown has not been reported until now. We have identified nine Mycobacterium smegmatis enzymes that utilize the… CONTINUE READING

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