Identification and characterization of the low-affinity receptor for immunoglobulin E (FcepsilonRII/CD23) on murine Langerhans cells.

@article{Nagaoka2002IdentificationAC,
  title={Identification and characterization of the low-affinity receptor for immunoglobulin E (FcepsilonRII/CD23) on murine Langerhans cells.},
  author={Yuzuru Nagaoka and Koichiro Nakamura and Nami Yasaka and Takahiro Watanabe and Akihiko Asahina and K. Shimoji T. Kurokawa T. Tamaki},
  journal={The Journal of investigative dermatology},
  year={2002},
  volume={119 1},
  pages={130-6}
}
CD23 is a low-affinity receptor for immunoglobulin E and expressed on various hemopoietic cells. Although human epidermal cultured Langerhans cells express CD23, the study to identify CD23 on murine Langerhans cells has so far failed. In this study, using highly enriched (> 95%) Langerhans cells from murine epidermis obtained by the panning method, we investigated whether murine Langerhans cells express CD23. As the result of a series of experiments using fluorescence activated cell sorter… CONTINUE READING