Identification and characterization of the major lysophosphatidylethanolamine acyltransferase in Saccharomyces cerevisiae.

@article{Riekhof2007IdentificationAC,
  title={Identification and characterization of the major lysophosphatidylethanolamine acyltransferase in Saccharomyces cerevisiae.},
  author={Wayne R. Riekhof and James Wu and Jennifer L. Jones and Dennis R. Voelker},
  journal={The Journal of biological chemistry},
  year={2007},
  volume={282 39},
  pages={28344-52}
}
We recently demonstrated that yeast actively import lysophosphatidylethanolamine (lyso-PtdEtn) through the action of plasma membrane P-type ATPases and rapidly acylate it to form PtdEtn. The predominant lyso-PtdEtn acyltransferase (LPEAT) activity present in cellular extracts is acyl-CoA dependent, but the identity of the gene encoding this activity was… CONTINUE READING