Identification and characterization of the human testes-specific protease 50 gene promoter.

@article{Wang2008IdentificationAC,
  title={Identification and characterization of the human testes-specific protease 50 gene promoter.},
  author={Miao Wang and Y. L. Bao and Yin Wu and Chun Lei Yu and Xiangying Meng and Hao Peng Xu and Yu-Xin Li},
  journal={DNA and cell biology},
  year={2008},
  volume={27 6},
  pages={307-14}
}
Testes-specific protease 50 (TSP50) has been identified as one of the testis-specific proteins that is expressed at high levels in approximately 92% of human breast cancer samples, making it an attractive molecular marker and a potential target for diagnosis and therapy. However, little is known about the transcriptional mechanisms controlling TSP50 gene expression. In the present study, we have characterized the 5' regulatory region of the TSP50 gene in order to understand the molecular… CONTINUE READING