Identification and characterization of sesaminol metabolites in the liver.

  title={Identification and characterization of sesaminol metabolites in the liver.},
  author={Mika Mochizuki and Yoshikazu Tsuchie and Yoshimasa Nakamura and Toshihiko Osawa},
  journal={Journal of agricultural and food chemistry},
  volume={57 21},
Sesame seeds contain a number of antioxidants, such as sesamin, sesamolin, sesaminol, and sesaminol glucosides. Sesaminol triglucoside was reported to suppress oxidative stress in vivo, but little is known about the metabolism of this potentially important compound. Therefore, we have studied the metabolites of sesaminol formed in the rat liver S9 mix and excreted in the liver of rats ingesting sesaminol triglucoside for 24 h. Nuclear magnetic resonance (NMR) and mass spectrometry (MS) analyses… CONTINUE READING