Identification and characterization of repopulating spermatogonial stem cells from the adult human testis.

@article{Izadyar2011IdentificationAC,
  title={Identification and characterization of repopulating spermatogonial stem cells from the adult human testis.},
  author={Fariborz Izadyar and Jadelind Wong and Chad B Maki and Jason Pacchiarotti and Thomas V Ramos and Kyle Howerton and Constance K Yuen and Scott Greilach and Hongyu Zhao and Michelle Chow and Y W Chow and J V Subba Rao and Jason Barritt and Natan Bar-Chama and Alan Barry Copperman},
  journal={Human reproduction},
  year={2011},
  volume={26 6},
  pages={1296-306}
}
BACKGROUND This study was conducted to identify and characterize repopulating spermatogonial stem cells (SSCs) in the adult human testes. METHODS Testes biopsies from obstructive azoospermic patients and normal segments of human testicular tissue were used. Flow cytometry, real-time PCR and immunohistochemical analysis were performed. Purified human… CONTINUE READING