Identification and characterization of potential impurities of amlodipine maleate.

@article{Sudhakar2006IdentificationAC,
  title={Identification and characterization of potential impurities of amlodipine maleate.},
  author={Padmaja Sudhakar and Muninarayanappa Nirmala and J. Moses Babu and Komal Vyas and Ganta Madhusudan Reddy and B Vijaya Bhaskar and P Pratap Reddy and Khagga Mukkanti},
  journal={Journal of pharmaceutical and biomedical analysis},
  year={2006},
  volume={40 3},
  pages={605-13}
}
Six impurities ranging from 0.43 to 1.42% in amlodipine maleate were detected by a simple isocratic reverse-phase high performance liquid chromatography (HPLC). LC-MS was performed to identify the mass of the impurities. Based on the spectral data (IR, NMR and MS), the structures of these impurities were characterized as 3-ethyl 5-methyl 4-(2-chlorophenyl… CONTINUE READING