Identification and characterization of oxidized human serum albumin

@article{Kawakami2006IdentificationAC,
  title={Identification and characterization of oxidized human serum albumin},
  author={Asami Kawakami and Kazuyuki Kubota and Naoyuki Yamada and Uno Tagami and Kenji Takehana and Ichiro Sonaka and Ei-Ichiro Suzuki and Kazuo Hirayama},
  journal={The FEBS Journal},
  year={2006},
  volume={273}
}
Human serum albumin (HSA) exists in both reduced and oxidized forms, and the percentage of oxidized albumin increases in several diseases. However, little is known regarding the pathophysiological significance of oxidation due to poor characterization of the precise structural and functional properties of oxidized HSA. Here, we characterize both the structural and functional differences between reduced and oxidized HSA. Using LC‐ESI‐TOFMS and FTMS analysis, we determined that the major… 
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