Identification and characterization of osteoclast progenitors by clonal analysis of hematopoietic cells

@inproceedings{Lee1992IdentificationAC,
  title={Identification and characterization of osteoclast progenitors by clonal analysis of hematopoietic cells},
  author={Minako Y. Lee and Jl Lottsfeldt and K L Fevold},
  year={1992}
}
  • Minako Y. Lee, Jl Lottsfeldt, K L Fevold
  • Published 1992
  • Biology
  • We have identified a distinct population of colony-forming cells that give rise to mononuclear cells expressing an enzyme marker and other features of the osteoclast in bone marrow cultures stimulated by conditioned medium of a murine tumor cell line. These colony-forming cells were defined as osteoclast colony-forming units (CFU-O). The tumor cell-derived activity was recently isolated and was named osteoclast colony-stimulating factor (O-CSF). To understand the development of osteoclast… CONTINUE READING

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