Identification and characterization of novel gut-associated lymphoid tissues in rat small intestine

@article{Hitotsumatsu2005IdentificationAC,
  title={Identification and characterization of novel gut-associated lymphoid tissues in rat small intestine},
  author={Osamu Hitotsumatsu and Hiromasa Hamada and Makoto Naganuma and Nagamu Inoue and Hiromasa Ashitani Noriaki Ishii and Toshifumi Hibi and Hiromichi Ishikawa},
  journal={Journal of Gastroenterology},
  year={2005},
  volume={40},
  pages={956-963}
}
The crypt lamina propria of the mouse small intestine has been shown to harbor multiple tiny clusters filled with c-kit- and interleukin 7 receptor (IL-7R)-positive lympho-hemopoietic cells (cryptopatches; CPs). However, it has remained an open question whether similar lymphoid tissue are present in the gastrointesitinal tract in other animals. In the present study, we investigated whether the small intestine of rats harbored lymphoid tissues similar to mouse CPs. Immunohistochemical and flow… CONTINUE READING
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