Identification and characterization of novel dermal Thy-1 antigen-bearing dendritic cells in murine skin.

@article{Tamaki1996IdentificationAC,
  title={Identification and characterization of novel dermal Thy-1 antigen-bearing dendritic cells in murine skin.},
  author={Kunihiko Tamaki and Nami Yasaka and Chung Hsing Chang and Naoki Ohtake and Akari Saitoh and Koichiro Nakamura and Masutaka Furue},
  journal={The Journal of investigative dermatology},
  year={1996},
  volume={106 3},
  pages={
          571-5
        }
}
Using immunofluorescence on dermal sheets of mouse ear, we identified novel Thy-1+ dermal dendritic cells in murine skin. These cells are resistant to topical corticosteroid treatment. The number of these dermal Thy-1+ dendritic cells is not altered with aging of the mice or with 3 d of culture. Dermal Thy-1+ dendritic cells have melanosomes in their cytoplasm; hence, phagocytic activity is likely to be present. Double immunofluorescence revealed that most of these dermal Thy-1+ dendritic cells… CONTINUE READING

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