Identification and characterization of muscarinic acetylcholine receptor subtypes expressed in human skin melanocytes

@article{Buchli2004IdentificationAC,
  title={Identification and characterization of muscarinic acetylcholine receptor subtypes expressed in human skin melanocytes},
  author={R. Buchli and A. Ndoye and J. Arredondo and R. Webber and S. Grando},
  journal={Molecular and Cellular Biochemistry},
  year={2004},
  volume={228},
  pages={57-72}
}
The present study was designed to identify and characterize muscarinic acetylcholine receptors in normal human melanocytes. We used subtype-specific oligonucleotide primers to localize the five genetically defined mAChR mRNAs (m1 through m5) by reverse transcription-polymerase chain reaction. These experiments showed that all five mAChR subtype mRNAs are expressed in melanocytes. The PCR products were verified by restriction analysis and Southern blotting. Receptors were visualized in cultures… Expand
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