Identification and characterization of human Fas associated factor 1, hFAF1.

  title={Identification and characterization of human Fas associated factor 1, hFAF1.},
  author={S W Ryu and Suhn Kee Chae and Kara J Lee and Eunmin Kim},
  journal={Biochemical and biophysical research communications},
  volume={262 2},
We have identified and characterized a cDNA encoding human Fas associated factor 1 (hFAF1) cDNA and a shorter form of hFAF1 cDNA [hFAF1(s)] with a 456 bp internal in-frame deletion from a human HeLa cDNA library. The nucleotide sequences of hFAF1 and hFAF1(s) were identical except for the deletion. GST-hFAF1 fusion protein bound to the in vitro translation product of Fas. The N-terminal region (amino acid 1 approximately 201) including the upstream ubiquitin homology domain of hFAF1 could bind… CONTINUE READING

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