Identification and characterization of anticancer compounds targeting apoptosis and autophagy from Chinese native Garcinia species.

@article{Xu2014IdentificationAC,
  title={Identification and characterization of anticancer compounds targeting apoptosis and autophagy from Chinese native Garcinia species.},
  author={Danqing Xu and Yuanzhi Lao and Naihan Xu and Hui Hu and Wenwei Fu and Hongsheng Tan and Yunzhi Gu and Zhijun Song and Peng Cao and Hongxi Xu},
  journal={Planta medica},
  year={2014},
  volume={81 1},
  pages={
          79-89
        }
}
  • Danqing Xu, Yuanzhi Lao, +7 authors Hongxi Xu
  • Published in Planta medica 2014
  • Medicine, Biology
  • Natural compounds from medicinal plants are important resources for drug development. Active compounds targeting apoptosis and autophagy are candidates for anti-cancer drugs. In this study, we collected Garcinia species from China and extracted them into water or ethanol fractions. Then, we performed a functional screen in search of novel apoptosis and autophagy regulators. We first characterized the anti-proliferation activity of the crude extracts on multiple cell lines. HeLa cells expressing… CONTINUE READING

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