Identification and characterization of a laminin-binding protein of Aspergillus fumigatus: extracellular thaumatin domain protein (AfCalAp).

@article{Upadhyay2009IdentificationAC,
  title={Identification and characterization of a laminin-binding protein of Aspergillus fumigatus: extracellular thaumatin domain protein (AfCalAp).},
  author={Santosh Kumar Upadhyay and Lakshna Mahajan and Sandhya Ramjee and Yogendra Singh and Seemi Farhat Basir and Taruna Madan},
  journal={Journal of medical microbiology},
  year={2009},
  volume={58 Pt 6},
  pages={714-22}
}
Aspergillus fumigatus, an opportunistic fungal pathogen, infects the human host via inhalation of airborne conidia. Adhesion of fungal conidia, to host cells and extracellular matrix (ECM) components associated with host tissue surfaces, is thought to be the primary step in the pathogenesis and dissemination of infection. To identify novel adhesion proteins (adhesins) of A. fumigatus, we screened its proteome in silico using SPAAN (software program for prediction of adhesins and adhesin-like… CONTINUE READING

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