Identification and characterization of a novel gastric peptide hormone: the motilin-related peptide.

  title={Identification and characterization of a novel gastric peptide hormone: the motilin-related peptide.},
  author={C. Tomasetto and S. Karam and S. Ribieras and R. Masson and O. Lefebvre and A. Staub and G. Alexander and Marie‐Pierre Chenard and M. Rio},
  volume={119 2},
  • C. Tomasetto, S. Karam, +6 authors M. Rio
  • Published 2000
  • Biology, Medicine
  • Gastroenterology
  • BACKGROUND & AIMS This study looked for new proteins with expression restricted to the gastric epithelium that may provide insight to the differentiation and function of the gastric unit. METHODS A novel complementary DNA was isolated and sequenced, and its expression was examined in mouse tissues at both messenger RNA and protein levels. Subcellular localization was studied using immunoelectron microscopy. The posttraductional processing of the protein was analyzed in vitro by protein… CONTINUE READING
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