Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor beta.

Abstract

We had previously identified the cDNA for a novel protein called osteoblast-specific factor 2 (OSF-2) from an MC3T3-E1 cDNA library using subtraction hybridization and differential screening techniques. Here we describe the localization, regulation, and potential function of this protein. Immunohistochemistry using specific antiserum revealed that in adult… (More)

Topics

Cite this paper

@article{Horiuchi1999IdentificationAC, title={Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor beta.}, author={Keisuke Horiuchi and Norio Amizuka and Satoshi Takeshita and Hitoshi Takamatsu and Mieko Katsuura and Hiroshi Ozawa and Yoshiro Toyama and Lynda F. Bonewald and Akira Kudo}, journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research}, year={1999}, volume={14 7}, pages={1239-49} }