Identification and characterization of a novel member of the fibroblast growth factor family.

@article{Greene1998IdentificationAC,
  title={Identification and characterization of a novel member of the fibroblast growth factor family.},
  author={Justina M. Greene and Yu Li Li and Pamela A. Yourey and Jens Gruber and Kenneth C. Carter and Brenda K Shell and Patrick A. Dillon and C. H. Florence and D Roxanne Duan and Ashley Hay-Ming Blunt and David M Ornitz and Steven M. Ruben and Ralph F. Alderson},
  journal={The European journal of neuroscience},
  year={1998},
  volume={10 5},
  pages={1911-25}
}
A new member of the fibroblast growth factor (FGF) family, FGF-13, has been molecularly cloned as a result of high throughput sequencing of a human ovarian cancer cell library. The open reading frame of the novel human gene (1419 bp) encodes for a protein of 216 a.a. with a molecular weight of 22 kDa. The FGF-13 sequence contains an amino-terminal hydrophobic region of 23 a.a. characteristic of a signal secretion sequence. FGF-13 is most homologous, 70% similarity at the amino acid level, to… CONTINUE READING

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