Identification and characterization of a novel tick-borne flavivirus subtype in goats (Capra hircus) in Spain.

@article{Mansfield2015IdentificationAC,
  title={Identification and characterization of a novel tick-borne flavivirus subtype in goats (Capra hircus) in Spain.},
  author={Karen Mansfield and Ana Morales and Nicholas Johnson and Nieves Ayll{\'o}n and Ursula H{\"o}fle and Pilar Alberdi and Isabel G Fern{\'a}ndez de Mera and Juan Francisco Garc{\'i}a Mar{\'i}n and Christian Gort{\'a}zar and Jos{\'e} de la Fuente and Anthony R. Fooks},
  journal={The Journal of general virology},
  year={2015},
  volume={96 Pt 7},
  pages={
          1676-81
        }
}
In 2011, a neurological disease was reported in a herd of goats (Capra hircus) in Asturias, Spain. Initial sequencing identified the causative agent as louping ill virus (LIV). Subsequently, with the application of whole genome sequencing and phylogenetic analysis, empirical data demonstrates that the LIV-like virus detected is significantly divergent from LIV and Spanish sheep encephalitis virus (SSEV). This virus encoded an amino acid sequence motif at the site of a previously identified… 

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