Identification and characterization of a diamine exporter in colon epithelial cells.

@article{Uemura2008IdentificationAC,
  title={Identification and characterization of a diamine exporter in colon epithelial cells.},
  author={Takeshi Uemura and Hagit F Yerushalmi and George Tsaprailis and David E Stringer and Kirk E Pastorian and Leo Hawel and Craig V. Byus and Eugene W. Gerner},
  journal={The Journal of biological chemistry},
  year={2008},
  volume={283 39},
  pages={26428-35}
}
SLC3A2, a member of the solute carrier family, was identified by proteomics methods as a component of a transporter capable of exporting the diamine putrescine in the Chinese hamster ovary (CHO) cells selected for resistance to growth inhibition by high exogenous concentrations of putrescine. Putrescine transport was increased in inverted plasma membrane vesicles prepared from cells resistant to growth inhibition by putrescine compared with transport in inverted vesicles prepared from non… CONTINUE READING
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