Identification and characterization of a multidomain hyperthermophilic cellulase from an archaeal enrichment.

@article{Graham2011IdentificationAC,
  title={Identification and characterization of a multidomain hyperthermophilic cellulase from an archaeal enrichment.},
  author={Joel E Graham and Melinda E Clark and Dana C Nadler and Sarah Huffer and Harshal A. Chokhawala and Sara E. Rowland and Harvey W. Blanch and Douglas A S Clark and Frank T Robb},
  journal={Nature communications},
  year={2011},
  volume={2},
  pages={375}
}
Despite extensive studies on microbial and enzymatic lignocellulose degradation, relatively few Archaea are known to deconstruct crystalline cellulose. Here we describe a consortium of three hyperthermophilic archaea enriched from a continental geothermal source by growth at 90 °C on crystalline cellulose, representing the first instance of Archaea able to deconstruct lignocellulose optimally above 90 °C. Following metagenomic studies on the consortium, a 90 kDa, multidomain cellulase… CONTINUE READING
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