Identification and characterization of a baboon reovirus-specific nonstructural protein encoded by the bicistronic s4 genome segment.

@article{Dawe2002IdentificationAC,
  title={Identification and characterization of a baboon reovirus-specific nonstructural protein encoded by the bicistronic s4 genome segment.},
  author={Sandra J Dawe and Julie Boutilier and Roy Duncan},
  journal={Virology},
  year={2002},
  volume={304 1},
  pages={44-52}
}
All characterized orthoreoviruses encode a characteristic spike-like protein on their polycistronic S1 genome segments that mediates virus cell attachment. In the case of baboon reovirus (BRV), the polycistronic S-class genome segment corresponds to the smallest S4 segment. We recently determined that the 5'-proximal open reading frame (ORF) of the bicistronic S4 segment encodes a nonstructural protein responsible for virus-induced syncytium formation. Current analysis indicates that the p16… CONTINUE READING

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