Identification and characterization of a prostaglandin transporter.

@article{Kanai1995IdentificationAC,
  title={Identification and characterization of a prostaglandin transporter.},
  author={Naoaki Kanai and Run Long Lu and James Satriano and Yi Zhong Bao and Allan W. Wolkoff and Victor L. Schuster},
  journal={Science},
  year={1995},
  volume={268 5212},
  pages={866-9}
}
Carrier-mediated prostaglandin transport has been postulated to occur in many tissues. On the basis of sequence homology, the protein of unknown function encoded by the rat matrin F/G complementary DNA was predicted to be an organic anion transporter. Expression of the matrin F/G complementary DNA in HeLa cells or Xenopus oocytes conferred the property of specific transport of prostaglandins. The tissue distribution of matrin F/G messenger RNA and the sensitivity of matrin F/G-induced… CONTINUE READING
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