Identification and characterization of SirA, an iron-regulated protein from Staphylococcus aureus.

@article{Heinrichs1999IdentificationAC,
  title={Identification and characterization of SirA, an iron-regulated protein from Staphylococcus aureus.},
  author={John H. Heinrichs and L E Gatlin and C Kunsch and Gil H. Choi and Mark S. Hanson},
  journal={Journal of bacteriology},
  year={1999},
  volume={181 5},
  pages={1436-43}
}
The acquisition of iron by pathogenic bacteria is often a crucial step in establishing infection. To accomplish this, many bacteria, including Staphylococcus aureus, produce low-molecular-weight iron-chelating siderophores. However, the secretion and transport of these molecules in gram-positive organisms are poorly understood. The sequence, organization, and regulation of genes involved in siderophore transport are conserved among gram-negative bacteria. We used this information to identify a… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

Similar Papers

Loading similar papers…