Identification and characteristics of microRNAs from Bombyx mori

@article{He2008IdentificationAC,
  title={Identification and characteristics of microRNAs from Bombyx mori},
  author={Ping-An He and Zuo-Ming Nie and Jianqing Chen and Jiangchuan Chen and Zhengbing Lv and Qing Sheng and Songping Zhou and Xiaolian Gao and Lingyin Kong and Xiang-fu Wu and Yongfeng Jin and Yao-Zhou Zhang},
  journal={BMC Genomics},
  year={2008},
  volume={9},
  pages={248 - 248}
}
MicroRNAs (miRNAs) are small RNA molecules that regulate gene expression by targeting messenger RNAs (mRNAs) and causing mRNA cleavage or translation blockage. Of the 355 Arthropod miRNAs that have been identified, only 21 are B. mori miRNAs that were predicted computationally; of these, only let-7 has been confirmed by Northern blotting. Combining a computational method based on sequence homology searches with experimental identification based on microarray assays and Northern blotting, we… CONTINUE READING

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