Identification and characterisation of a multidrug resistance-related protein mRNA in the blue mussel Mytilus edulis

@inproceedings{Luedeking2005IdentificationAC,
  title={Identification and characterisation of a multidrug resistance-related protein mRNA in the blue mussel Mytilus edulis},
  author={Alexander Luedeking and Cornelis J. F. van Noorden and Angela Koehler},
  year={2005}
}
Membrane-associated transport proteins were discovered in the 1970s in mammals and were considered to be expressed in response to chemotherapy during cancer treatment. Prominent members of this class of proteins are multidrug resistance-related or -associated proteins (MRPs). Besides their expression in cancer cells, MRPs are ubiquitously expressed in normal tissues and are active transporters of reduced glutathione, glucuronate and organic anions of toxicological relevance, either conjugated… CONTINUE READING
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