Identification and biochemical studies on novel non-nucleoside inhibitors of the enzyme adenosine kinase.

Abstract

The enzyme adenosine kinase (AK) plays a key role in the regulation of intracellular and extracellular concentration of adenosine (Ado), which exhibits potent hormonal activity in cardiovascular, nervous and immune systems. In view of the pharmacological effects of Ado, there is much interest in identifying inhibitors of AK, which can augment its tissue… (More)

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@article{Park2007IdentificationAB, title={Identification and biochemical studies on novel non-nucleoside inhibitors of the enzyme adenosine kinase.}, author={Jae Park and Gayathri Vaidyanathan and Bhag Singh and Radhey S Gupta}, journal={The protein journal}, year={2007}, volume={26 3}, pages={203-12} }