Identification and activation of mitogen-activated protein (MAP) kinase in normal human osteoblastic and bone marrow stromal cells: Attenuation of MAP kinase activation by cAMP, parathyroid hormone and forskolin

@article{Chaudhary1998IdentificationAA,
  title={Identification and activation of mitogen-activated protein (MAP) kinase in normal human osteoblastic and bone marrow stromal cells: Attenuation of MAP kinase activation by cAMP, parathyroid hormone and forskolin},
  author={Lala R. Chaudhary and Louis V. Avioli},
  journal={Molecular and Cellular Biochemistry},
  year={1998},
  volume={178},
  pages={59-68}
}
The mitogen-activated protein (MAP) kinases (p44mapk and p42mapk), also known as extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2), are activated in response to a variety of extracellular signals, including growth factors, hormones and, neurotransmitters. We have investigated MAP kinase signal transduction pathways in normal human osteoblastic cells. Normal human bone marrow stromal (HBMS), osteoblastic (HOB), and human (TE85, MG-63, SaOS-2), rat (ROS 17/2.8, UMR-106) and mouse… CONTINUE READING
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Identification and regulation of PHASI protein by PDGFBB and basic FGF in normal human osteoblastic cells

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