Identification and Functional Characterization of Hypoxia-Induced Endoplasmic Reticulum Stress Regulating lncRNA (HypERlnc) in Pericytes

@article{Bischoff2017IdentificationAF,
  title={Identification and Functional Characterization of Hypoxia-Induced Endoplasmic Reticulum Stress Regulating lncRNA (HypERlnc) in Pericytes},
  author={Florian C Bischoff and A. Werner and D. John and J. Boeckel and M. Melissari and Phillip Grote and Simone F. Glaser and Shemsi Demolli and Shizuka Uchida and K. Michalik and B. Meder and H. Katus and Jan Haas and Wei Chen and S. Pullamsetti and W. Seeger and A. Zeiher and S. Dimmeler and C. Zehendner},
  journal={Circulation Research},
  year={2017},
  volume={121},
  pages={368–375}
}
Rationale: Pericytes are essential for vessel maturation and endothelial barrier function. Long noncoding RNAs regulate many cellular functions, but their role in pericyte biology remains unexplored. Objective: Here, we investigate the effect of hypoxia-induced endoplasmic reticulum stress regulating long noncoding RNAs (HypERlnc, also known as ENSG00000262454) on pericyte function in vitro and its regulation in human heart failure and idiopathic pulmonary arterial hypertension. Methods and… Expand
LncRNAs in vascular biology and disease.
Circular RNA-ZNF532 regulates diabetes-induced retinal pericyte degeneration and vascular dysfunction.
Down-regulation of lncRNA MEG3 promotes hypoxia-induced human pulmonary artery smooth muscle cell proliferation and migration via repressing PTEN by sponging miR-21.
Long noncoding RNAs: emerging roles in pulmonary hypertension
Long noncoding RNAs as novel players in the pathogenesis of hypertension
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References

SHOWING 1-10 OF 41 REFERENCES
Long Noncoding RNA MALAT1 Regulates Endothelial Cell Function and Vessel Growth
Long Noncoding RNAs in Cardiovascular Diseases
Identification and Initial Functional Characterization of a Human Vascular Cell–Enriched Long Noncoding RNA
The long noncoding RNA landscape in hypoxic and inflammatory renal epithelial injury.
Long Noncoding RNAs: From Clinical Genetics to Therapeutic Targets?
...
1
2
3
4
5
...