• DOI:10.1161/CIRCRESAHA.116.310531
Corpus ID: 13332981

Identification and Functional Characterization of Hypoxia-Induced Endoplasmic Reticulum Stress Regulating lncRNA (HypERlnc) in Pericytes

@article{Bischoff2017IdentificationAF,
  title={Identification and Functional Characterization of Hypoxia-Induced Endoplasmic Reticulum Stress Regulating lncRNA (HypERlnc) in Pericytes},
  author={Florian C Bischoff and A. Werner and D. John and J. Boeckel and M. Melissari and Phillip Grote and Simone F. Glaser and Shemsi Demolli and Shizuka Uchida and K. Michalik and B. Meder and H. Katus and Jan Haas and Wei Chen and S. Pullamsetti and W. Seeger and A. Zeiher and S. Dimmeler and C. Zehendner},
  journal={Circulation Research},
  year={2017},
  volume={121},
  pages={368–375}
}

• Florian C Bischoff, A. Werner, +16 authors C. Zehendner
• Published 2017
• Biology, Medicine
• Circulation Research

Rationale: Pericytes are essential for vessel maturation and endothelial barrier function. Long noncoding RNAs regulate many cellular functions, but their role in pericyte biology remains unexplored. Objective: Here, we investigate the effect of hypoxia-induced endoplasmic reticulum stress regulating long noncoding RNAs (HypERlnc, also known as ENSG00000262454) on pericyte function in vitro and its regulation in human heart failure and idiopathic pulmonary arterial hypertension. Methods and… Expand

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