Identification and Functional Analysis of Genome Mutations in a Fluoride-Resistant Streptococcus mutans Strain


It is known that fluoride-resistant microorganisms are different from fluoride-sensitive ones in growth, adherence and metabolic activity. It was hypothesized that these phenotypic differences were due to stable genotypic changes in the fluoride-resistant strains. However, until now, no studies have reported these genotypic changes. The aim of this study is… (More)
DOI: 10.1371/journal.pone.0122630


6 Figures and Tables