Identification and Characterization of the OCT4 Upstream Regulatory Region in Sus scrofa

@inproceedings{Kim2019IdentificationAC,
  title={Identification and Characterization of the OCT4 Upstream Regulatory Region in Sus scrofa
},
  author={Seung-hun Kim and Kwang-Hwan Choi and Dong-Kyung Lee and Mingyun Lee and Jae Yeon Hwang and Chang-kyu Lee},
  booktitle={Stem cells international},
  year={2019}
}
OCT4 plays pivotal roles in maintaining pluripotency during early mammalian embryonic development and in embryonic stem cells. It is essential to establish a reporter system based on the OCT4 promoter region to study pluripotency. However, there is still a lack of information about the porcine OCT4 upstream reporter system. To improve our understanding of the porcine OCT4 regulatory region, we identified conserved regions in the porcine OCT4 promoter upstream region by sequence-based… CONTINUE READING