Identification and Characterization of an Insulin-Like Receptor Involved in Crustacean Reproduction.

@article{Sharabi2016IdentificationAC,
  title={Identification and Characterization of an Insulin-Like Receptor Involved in Crustacean Reproduction.},
  author={Omri Sharabi and Rivka Manor and Simy Weil and Eliahu David Aflalo and Y Lezer and Tom Levy and Joseph Aizen and Tomer Ventura and Peter B. Mather and Isam Khalaila and Amir Sagi},
  journal={Endocrinology},
  year={2016},
  volume={157 2},
  pages={928-41}
}
Sexual differentiation and maintenance of masculinity in crustaceans has been suggested as being regulated by a single androgenic gland (AG) insulin-like peptide (IAG). However, downstream elements involved in the signaling cascade remain unknown. Here we identified and characterized a gene encoding an insulin-like receptor in the prawn Macrobrachium rosenbergii (Mr-IR), the first such gene detected in a decapod crustacean. In mining for IRs and other insulin signaling-related genes, we… CONTINUE READING

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