Identification and Characterization of a Lysophosphatidylcholine Acyltransferase That is Primarily Expressed in Metabolic Tissues

@inproceedings{Zhao2008IdentificationAC,
  title={Identification and Characterization of a Lysophosphatidylcholine Acyltransferase That is Primarily Expressed in Metabolic Tissues},
  author={Yang Zhao and Yanqun Chen and Tabetha M. Bonacci and David S. Bredt and Shuyu Li and William R. Bensch and David Moller and Mark C. Kowala and Robert J. Konrad and Guoqing Cao},
  year={2008}
}
Phosphatidylcholine (PC) is synthesized through the Kennedy pathway but more than 50% of PC is remodeled through Lands cycle, i.e. the deacylation and reacylation of PC to attain the final and proper fatty acids within PC. The reacylation step is catalyzed by lysophosphatidylcholine (LPC) acyltransferase (LPCAT) and we report here the identification of a novel LPCAT, which we named LPCAT3. LPCAT3 belongs to the membrane bound Oacyltransferase (MBOAT) family and encodes a protein of 487 amino… CONTINUE READING