Identification and Characterization of a Novel IL-4 Receptor α Chain ( IL-4 R α ) Antagonist to Inhibit IL-4 Signalling

  • Nayyar Ahmeda Pathum Dhanapalaa, Cenk Suphioglua
  • Published 2015


Background/Aims: In recent times, allergy has become a financial, physical and psychological burden to the society as a whole. In allergic cascades, cytokine IL-4 binds to IL-4 receptor (IL4R), consequently producing allergen-specific IgE antibodies by B cells. In addition, among other functions, IL-4 is also responsible for B and T cell proliferation and… (More)

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