Identification and Characterization of Two Klebsiella pneumoniae lpxL Lipid A Late Acyltransferases and Their Role in Virulence.

Abstract

Klebsiella pneumoniae causes a wide range of infections, from urinary tract infections to pneumonia. The lipopolysaccharide is a virulence factor of this pathogen, although there are gaps in our understanding of its biosynthesis. Here we report on the characterization of K. pneumoniaelpxL, which encodes one of the enzymes responsible for the late secondary… (More)
DOI: 10.1128/IAI.00068-17

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@article{Mills2017IdentificationAC, title={Identification and Characterization of Two Klebsiella pneumoniae lpxL Lipid A Late Acyltransferases and Their Role in Virulence.}, author={Grant Mills and Amy Dumigan and Timothy J Kidd and Laura Hobley and Jos{\'e} A Bengoechea}, journal={Infection and immunity}, year={2017}, volume={85 9} }