Identification, synthesis and biological activity of alkyl-guanidine oligomers as potent antibacterial agents

@inproceedings{Zamperini2017IdentificationSA,
  title={Identification, synthesis and biological activity of alkyl-guanidine oligomers as potent antibacterial agents},
  author={Claudio Zamperini and Giorgio Maccari and Davide Deodato and C Pasero and I D'Agostino and F Orofino and Filomena De Luca and Elena Dreassi and J D Docquier and Maurizio Botta},
  booktitle={Scientific Reports},
  year={2017}
}
In the last two decades, the repertoire of clinically effective antibacterials is shrinking due to the rapidly increasing of multi-drug-resistant pathogenic bacteria. New chemical classes with innovative mode of action are required to prevent a return to the pre-antibiotic era. We have recently reported the identification of a series of linear guanidine… CONTINUE READING