Identification, characterization, and molecular application of a virulence-associated autotransporter from a pathogenic Pseudomonas fluorescens strain.

@article{Hu2009IdentificationCA,
  title={Identification, characterization, and molecular application of a virulence-associated autotransporter from a pathogenic Pseudomonas fluorescens strain.},
  author={Yong-Hua Hu and Chun-sheng Liu and Jin-hui Hou and Li Sun},
  journal={Applied and environmental microbiology},
  year={2009},
  volume={75 13},
  pages={
          4333-40
        }
}
A gene, pfa1, encoding an autotransporter was cloned from a pathogenic Pseudomonas fluorescens strain, TSS, isolated from diseased fish. The expression of pfa1 is enhanced during infection and is regulated by growth phase and growth conditions. Mutation of pfa1 significantly attenuates the overall bacterial virulence of TSS and impairs the abilities of TSS in biofilm production, interaction with host cells, modulation of host immune responses, and dissemination in host blood. The putative… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 61 REFERENCES

Immunoprotective analysis of two Edwardsiella tarda antigens.

  • The Journal of general and applied microbiology
  • 2009
VIEW 3 EXCERPTS