Identical amyloid precursor proteins in two breeds of chickens which differ in susceptibility to develop amyloid arthropathy.

@article{Ovelgnne2001IdenticalAP,
  title={Identical amyloid precursor proteins in two breeds of chickens which differ in susceptibility to develop amyloid arthropathy.},
  author={J. H. Ovelg{\"o}nne and Wil J. M. Landman and Erik Gruys and Arno L. J. Gielkens and Ben Peeters},
  journal={Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis},
  year={2001},
  volume={8 1},
  pages={
          41-51
        }
}
Chickens (Gallus gallus domesticus) can suffer from AA amyloidosis featuring the joints as major targets of amyloid accumulation. Analysis of post-mortem recordings from commercial chickens revealed that amyloid arthropathy frequently occurred in brown layer chickens, but never in white layers. The suspected higher susceptibility of brown layers was confirmed experimentally by inducing amyloidosis with an arthropathic and amyloidogenic strain of E. faecalis. Sequence analysis of cDNA coding for… CONTINUE READING

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