Identi fi cation of b-hematin inhibitors in the MMV Malaria Box

@inproceedings{Fong2015IdentiFC,
  title={Identi fi cation of b-hematin inhibitors in the MMV Malaria Box},
  author={Kim Yuen Fong and Rebecca D. Sandlin and David W. Wright},
  year={2015}
}
The Malaria Box, assembled by the Medicines for Malaria Venture, is a set of 400 structurally diverse, commercially available compounds with demonstrated activity against blood-stage Plasmodium falciparum. The compounds are a representative subset of the 20,000 in vitro antimalarials identified from the high-throughput screening efforts of St. Jude Children's Research Hospital (TN, USA), Novartis and GlaxoSmithKline. In addition, a small set of active compounds from commercially available… CONTINUE READING

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