Id-1 induces proteasome-dependent degradation of the HBX protein.

  title={Id-1 induces proteasome-dependent degradation of the HBX protein.},
  author={M. L. Ling and Yung-Tuen Chiu and Terence Kin-Wah Lee and Steve Chin Lung Leung and Maggie Ka Lai Fung and Xianghong Wang and Kwong Fai Wong and Y. -C. Wong},
  journal={Journal of molecular biology},
  volume={382 1},
Id-1 is a member of the HLH protein family that regulates a wide range of cellular processes such as cell proliferation, apoptosis, senescence and overexpression of Id-1 was recently suggested to play roles in the development and progression of different cancers. Previously, Id-1 was shown to physically interact with the viral protein E1A. Meanwhile, Id-1 expression was found to be regulated by several of the virus-encoded proteins, suggesting that Id-1 may be a common cellular target of the… CONTINUE READING


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