Ictal laughter associated with paroxysmal hypothalamopituitary dysfunction.

  title={Ictal laughter associated with paroxysmal hypothalamopituitary dysfunction.},
  author={Santiago Arroyo and Joan Santamar{\'i}a and F Sanmart{\'i} and Francisco Lome{\~n}a and Ana M. Catafau and Roser Casamitjana and Jordi Setoain and Eduard Tolosa},
  volume={38 1},
PURPOSE Seizures with ictal laughter (also termed gelastic seizures) have been associated with hypothalamic hamartomas and precocious puberty. It is not known, however, where in the brain such seizures originate. We describe a child with gelastic seizures and a hypothalamic lesion (probably a hamartoma) in whom two dysfunctional phenomena were observed. RESULTS First, there was a hyperperfusion in the hypothalamopituitary areas shown by ictal [99m]Tc hexamethyl-propyleneamine oxime (HM-PAO… CONTINUE READING


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