Icodextrin metabolism and alpha-amylase activity in nonuremic rats undergoing chronic peritoneal dialysis.

@article{GarcaLpez2007IcodextrinMA,
  title={Icodextrin metabolism and alpha-amylase activity in nonuremic rats undergoing chronic peritoneal dialysis.},
  author={Elvia Garc{\'i}a-L{\'o}pez and Krzysztof Pawlaczyk and Bj{\"o}rn Anderstam and Abdul Rashid Qureshi and Malgorzata Kuzlan-Pawlaczyk and Olof Heimb{\"u}rger and Andrzej Werynski and Bengt Lindholm},
  journal={Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis},
  year={2007},
  volume={27 4},
  pages={415-23}
}
OBJECTIVE To study the metabolism of icodextrin and alpha-amylase activity following daily exposure to dialysis solutions containing either glucose or icodextrin as osmotic agent in rats. METHODS Male Wistar rats with implanted peritoneal catheters were infused twice daily for 3 weeks with 20 mL 7.5% icodextrin-based peritoneal dialysis fluid (IPDF; ICO group, n = 12) or 3.86% glucose-based peritoneal dialysis fluid (GLU group, n = 11). A 4-hour dwell study using 30 mL IPDF was performed on… CONTINUE READING
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