Icatibant as an early rescue therapy in hypovolemic shock with converting enzyme inhibitor treatment

@inproceedings{Charbonneau2017IcatibantAA,
  title={Icatibant as an early rescue therapy in hypovolemic shock with converting enzyme inhibitor treatment},
  author={H{\'e}l{\`e}ne Charbonneau and Marie Bul{\'e}on and Benoit Richard and Nicolas Mayeur},
  booktitle={Critical care},
  year={2017}
}
Activation of the renin-angiotensin system is a key adaptive response to hypovolemia aiming at maintaining mean arterial pressure, cardiac output, and organ perfusion. Angiotensin converting enzyme inhibitor (ACEI) therapy, widely prescribed to treat chronic hypertension, chronic heart disease, or diabetic nephropathy, blunts this adaptive mechanism [1… CONTINUE READING