Icariin promotes early and late stages of fracture healing in rats.

@article{Grbz2019IcariinPE,
  title={Icariin promotes early and late stages of fracture healing in rats.},
  author={Kaan G{\"u}rb{\"u}z and M{\"u}kerrem Bet{\"u}l Yerer and Perihan G{\"u}rb{\"u}z and Mehmet G{\"o}khan Halıcı},
  journal={Eklem hastaliklari ve cerrahisi = Joint diseases \& related surgery},
  year={2019},
  volume={30 3},
  pages={
          282-8
        }
}
OBJECTIVES This study aims to evaluate the effects of locally applied icariin on bone fracture healing in femur fractured rat model. MATERIALS AND METHODS The study included 64 male Sprague-Dawley rats (mean age 6 months; weighing, 280-490 g) in eight main study groups. Fracture healing process and level were evaluated with radiography, histopathology and dual energy X-ray absorptiometry to investigate the effects of local administration of icariin at varying doses, which is an exogenous… 

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