Icariin impacts molecular changes in estrogen receptors but not other reproductive parameters in female mice

  title={Icariin impacts molecular changes in estrogen receptors but not other reproductive parameters in female mice},
  author={Caroline W. Muneri and Seth Yaw Afedo and Yaping Xu and Guochao Ni and Qing-Hua Shen and Rong Rui},
  journal={Indian Journal of Animal Research},
This study was conducted to assess the effects of icariin (ICA) an ingredient of Epimedium species, on reproductive parameters in mice. Serum, uterus and ovarian samples were collected after treatment. We determined the reproductive index (RI) and in vitro maturation (IVM) rates of oocytes. The serum was tested for 17b-estradiol (17b-E2) and progesterone (P4) using radioimmunoassay (RIA) and ovaries were analyzed for mRNA expression of Steroidogenic acute regulatory protein (Star), Cytochrome… 

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