Corpus ID: 112714872

Ibuprofene e cortisone a confronto: rischio e beneficio di utilizzo in termini di efficacia e safety Ibuprofen versus steroids: risk and benefit, efficacy and safety

@inproceedings{Giovannini2013IbuprofeneEC,
  title={Ibuprofene e cortisone a confronto: rischio e beneficio di utilizzo in termini di efficacia e safety Ibuprofen versus steroids: risk and benefit, efficacy and safety},
  author={Marcello Giovannini and Marzia Mandelli and C N Gualdi and Steven Palazzo},
  year={2013}
}
Negli ultimi anni si e osservata una graduale sempre maggiore attitudine all’uso pediatrico dell’ibuprofene per il trattamento antiinfiammatorio e antipiretico. Il pediatra si trova quindi spesso a poter scegliere una valida alternativa rispetto a cortisonici e paracetamolo, nel trattamento di stati infiammatori e febbrili nel bambino. Nella pratica clinica e utilizzabile in caso di cefalea, odontalgia, otalgia, dismenorrea, nevralgie, dolori osteoarticolari, artromialgie, crampi addominali e… Expand

References

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Efficacy and Safety of Ibuprofen and Acetaminophen in Children and Adults: A Meta-Analysis and Qualitative Review
TLDR
Qualitative review of the literature revealed that, for the most part, ibuprofen was more efficacious than acetaminophen for the treatment of pain and fever in both pediatric and adult populations, and that these 2 drugs were equally safe. Expand
[Focus on the safety of ibuprofen at the analgesic-antipyretic dose].
TLDR
The favourable safety profile of ibuprofen may be related to short term use of low doses in otherwise healthy young patients, associated to a short product half-life, and may be to specific product properties. Expand
Effects of Corticosteroid on Henoch-Schönlein Purpura: A Systematic Review
TLDR
A meta-analysis based on a comprehensive review of the literature in the Medline database and the Cochrane Controlled Trials Register found corticosteroid treatment given early in the course of illness seem to produce consistent benefits for several major clinically relevant Henoch-Schönlein purpura outcomes. Expand
Efficacy and safety of acetaminophen vs ibuprofen for treating children's pain or fever: a meta-analysis.
TLDR
In children, single doses of ibuprofen and acetaminophen have similar efficacy for relieving moderate to severe pain, and similar safety as analgesics or antipyretics. Expand
Evaluation of ibuprofen versus aspirin and paracetamol on efficacy and comfort in children with fever
TLDR
The efficacy of ibuprofen was better than that of aspirin or paracetamol and in spite of more adverse events, the comfort scores were significantly in favour of ib uprofen 6 h after the first dose of treatment. Expand
The Safety of Acetaminophen and Ibuprofen Among Children Younger Than Two Years Old
TLDR
The risk of serious adverse clinical events among children <2 years old receiving short-term treatment with either acetaminophen or ibuprofen suspension was small and did not vary by choice of medication. Expand
On the various forms of corticosteroid withdrawal syndrome.
TLDR
Studies of hypothalmic-pituitary-adrenocortical (HPA) function in five patients who had received corticosteroids for periods of years experienced steroid withdrawal symptoms when attempts were made to reduce or discontinue the drugs. Expand
Paracetamol and ibuprofen for the treatment of fever in children: the PITCH randomised controlled trial.
TLDR
Paracetamol and ibuprofen together was the cheapest option for the NHS due to the lower use of health-care services and cheapest for parents because the lowerUse of health care services resulted in personal saving on travel costs and less time off work. Expand
The Therapeutic Effectiveness of Ibuprofen on the Symptoms of Naturally Acquired Common Colds
TLDR
The effect of a nonsteroidal anti-inflammatory drug (NSAID) ibuprofen, 400 mg three times daily, in a placebo-controlled trial of 80 adults with naturally occurring common colds caused a significant reduction of headache, earache, muscle/joint pain, and reduced body temperature. Expand
Effect of Long-term Corticosteroid Use on Bone Mineral Density in Children: A Prospective Longitudinal Assessment in the Childhood Asthma Management Program (CAMP) Study
TLDR
Inhaled corticosteroid use has the potential for reducing bone mineral accretion in male children progressing through puberty, but this risk is likely to be outweighed by the ability to reduce the amount of oral corticosterone used in these children. Expand
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